What is Hepatoblastoma?

Hepatoblastoma is a rare cancer that develops in the liver and is usually diagnosed in children under the age of 3. But it can be seen in children and adults of all ages.

Owing to the improvement in diagnosis and treatment methods, it is possible for hepatoblastoma patients to live longer. When diagnosing the disease, abdominal ultrasonography, computed tomography, magnetic rasonance imaging techniques are used. In addition, SIOPEL (International Childhood Liver Tumors Strategy Group) recommends preoperative chemotherapy for patients diagnosed with hepatoblastoma, while liver transplantation may be required for some patients.


What are the Symptoms?

Hepatoblastoma is a type of cancer that does not show itself at first but shows symptoms as the tumor grows.

Symptoms of hepatoblastoma include:

  • Stomach ache
  • Abdominal bloating
  • Lump in the abdomen
  • Fever, itching
  • Diarrhea
  • Loss of appetite, nausea
  • Abnormal weight loss
  • Dark color of urine
  • Jaundice


What Are the Treatment Options for Hepatoblastoma?

Treatment of hepatoblastoma varies according to the stage of spread of the cancer, the size of the tumor and symptoms. The treatment options that can be applied are as follows:

  • Surgical treatment
  • Radiation
  • Chemotherapy
  • Medication
  • Liver transplant


Is Hepatoblastoma Genetic?

The exact cause of hepatoblastoma is unknown. However, some genetic diseases are known to increase the risk of hepatoblastoma. These genetic diseases are:

  • Wilson's disease
  • Porphyry Kutanya
  • Familial Adenomatous Polyposis
  • Beckwith-Wiedemann syndrome